【理学院】 Nature's Sniper for Long Range Specific Oxidation

报告题目:Nature's Sniper for Long Range Specific Oxidation

报告人 : Professor Liu Aimin

Department of Chemistry，College of Arts & Sciences，

Georgia State University，USA

报告时间：2014年11月7日 15:30

报告地点：行政楼一楼报告厅

欢迎参加！

Curriculum Vitae

Education

1997-1999：Ph.D.(Biochemistry), ArrheniusLaboratories for Natural Sciences, Stockholm University，Stockholm, Sweden.

1981-1986：B.S. (Chemistry), Departmentof Chemistry, University of Science and Technology of China, Hefei, P. R.China

Profession

1992-1996：Associate Professor, Department of Chemistry Xiamen University,P. R.China

1996-1997：Royal Society Research Fellow, Department of Chemistry Universityof Newcastle.

1999-2002：Postdoctoral and Research Associate, University of Minnesota，Minneapolis，MN

2002-2008：Associate Professor , Department of Bio-chemistry, University of Mississippi Medical Center, Jackson,M.S.

2008------：Professor, Department of Chemistry,Georgia State University, Atlanta,G.A.

Publication

1. Liu F, Rehmani I, Esaki S, Fu R, Chen L, Serroano V, and Liu A. Pirin is an iron-dependent redox regulator of NF-κB. Proc. Natl. Acad. Sci. U.S.A., 2013, 110(24), 9722-9727

2. Geng J, Dornevil K, Davidson VL, and Liu A. Tryptophan-mediated charge-resonance stabilization in the bis-Fe(IV) redox state of MauG. Proc. Natl. Acad. Sci. U.S.A., 2013, 110(24), 9639-9644

3. Yukl ET, Liu F, Krzystek J, Shin S, Jensen LMR, Davidson VL, Wilmot CM, and Liu A. Diradical intermediate within the context of tryptophan tryptophylquinone biosynthesis. Proc. Natl. Acad. Sci. U.S.A., 2013, 110(12), 4569-4573

4. Geng J, Dornevil K, and Liu A. Chemical rescue of the distal histidine mutants of tryptophan 2,3-dioxygenase. J. Am. Chem. Soc., 2012, 134(29), 12209-12218.

5. Tarboush NA, Jensen LMR, Yukl ET, Geng J, Liu A, Wilmot CM, and Davidson VL. Mutagenesis of tryptophan199 suggests that electron hopping is required for MauG-dependent tryptophan tryptophylquinone biosynthesis. Proc. Natl. Acad. Sci. U.S.A., 2011, 108(41), 16956-16961

6. Li X, Fu R, Lee S, Krebs C, Davidson VL, and Liu A. A catalytic di-heme bis-Fe(IV) form of MauG, Alternative to an Fe(IV)=O porphyrin radical. Proc. Natl. Acad. Sci. U.S.A., 2008, 105(25), 8597-8600

7. Li T, Ma J, Hosler JP, Davidson VL and Liu A. Detection of transient intermediates in the metal-dependent nonoxidative decarboxylation catalyzed by α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase.J. Am. Chem. Soc., 2007, 129(30), 9278-9279.

8. Li T, Walker AL, Iwaki H, Hasegawa Y, and Liu A. Kinetic and spectroscopic characterization of ACMSD from Pseudomonas fluorescens reveals a pentacoordinate mononuclear metallocofactor. J. Am. Chem. Soc., 2005, 127(35), 12282-12290.